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Search Results for " complement component 5 "

Targets Recommended: Complement System

5

抑制剂 & 化合物

17

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10863	Complement C5-IN-1	Complement System	Immunology/Inflammation
	Complement C5-IN-1 (Compound 7) 是补体成分蛋白5 (C5) 的小分子抑制剂。 Complement C5-IN-1 与 C5 相互作用以防止其被 C5 转化酶切割, 阻断酵母多糖诱导的 50％人全血 MAC 沉积的 IC50 值为 0.77 μM。
T76276	Zilucoplan
	Zilucoplan (RA101495)为含15个氨基酸的大环肽，兼作有效的补体成分5 (C5) 抑制剂，适用于免疫介导的坏死性肌病 (IMNM) 研究。
T80083	Zilucoplan TFA RA101495 TFA	Complement System	Immunology/Inflammation
	Zilucoplan TFA (RA101495)为含15个氨基酸的大环肽，有效抑制补体组分5 (C5)。该化合物适用于免疫介导的坏死性肌病 (IMNM) 研究。
T77121	Pozelimab
	Pozelimab (REGN3918)为一种针对component 5 (C5) 的人源IgG4单克隆抗体。其通过高亲和力结合C5及其变体，有效阻断补体介导的溶血作用，适用于对补体介导疾病进行研究。
T64692	AMY-101 acetate
	Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exerting direct effector functions, and helping to coordinate downstream immune responses[3]. In C3-/- mice alcohol-induced liver steatosis is absent or strongly reduced after chronic or acute alcohol exposure. This suggests that the complement system and its component C3 contribute...

化合物

Complement C5-IN-1

Cat.No: T10863

Target: Complement System

Cat.No: T76276

Cat.No: T80083

Synonym: RA101495 TFA

Target: Complement System

Cat.No: T77121

AMY-101 acetate

Cat.No: T64692

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04902	Complement C5a Protein, Mouse, Recombinant complement component 5	Mouse	E. coli
	Complement C5a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684.
TMPY-05057	Complement C5 Protein, Human, Recombinant (His & FLAG) C5b,ECLZB,C5a,CPAMD4,C5D,comp...	Human	HEK293 Cells
	Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 188.8 kDa and the accession number is P01031.
TMPY-00653	Complement C5 Protein, Human, Recombinant (Complement C5a) C5D,C5b,CPAMD4,complement com...	Human	E. coli
	Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is P01031.
TMPY-05731	Complement C3 Protein, Human, Recombinant (His) HEL-S-62p,CPAMD1,ARMD9,C3b,ASP,C3a,AHUS5,comple...	Human	HEK293 Cells
	Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024.
TMPY-06538	Complement C5 Protein, Cynomolgus, Recombinant complement component 5	Cynomolgus	HEK293 Cells
	Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.41 kDa and the accession number is XP_005580972.1.
TMPY-05459	Complement C5a Protein, Mouse, Recombinant, Biotinylated complement component 5	Mouse	E. coli
	Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684.
TMPY-06137	Complement C5 Protein, Cynomolgus, Recombinant (His) complement component 5	Cynomolgus	HEK293 Cells
	Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 188.1 kDa and the accession number is XP_005580972.1.
TMPY-06814	Complement C5 Protein, Human, Recombinant (Flag) C5a,CPAMD4,ECLZB,C5b,C5D,Comp...	Human	HEK293 Cells
	Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 187.36 kDa and the accession number is NP_001726.2.
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-01816	Pentraxin 3 Protein, Human, Recombinant (His) TNFAIP5,pentraxin 3,PTX3,TSG-14	Human	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cycl...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc) SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His) V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi) MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

Complement C5a Protein, Mouse, Recombinant

Cat.No: TMPY-04902

Species: Mouse

Expression System: E. coli

Complement C5 Protein, Human, Recombinant (His & FLAG)

Cat.No: TMPY-05057

Species: Human

Expression System: HEK293 Cells

Complement C5 Protein, Human, Recombinant (Complement C5a)

Cat.No: TMPY-00653

Species: Human

Expression System: E. coli

Complement C3 Protein, Human, Recombinant (His)

Cat.No: TMPY-05731

Species: Human

Expression System: HEK293 Cells

Complement C5 Protein, Cynomolgus, Recombinant

Cat.No: TMPY-06538

Species: Cynomolgus

Expression System: HEK293 Cells

Complement C5a Protein, Mouse, Recombinant, Biotinylated

Cat.No: TMPY-05459

Species: Mouse

Expression System: E. coli

Complement C5 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06137

Species: Cynomolgus

Expression System: HEK293 Cells

Complement C5 Protein, Human, Recombinant (Flag)

Cat.No: TMPY-06814

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

Pentraxin 3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01816

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05387

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05547

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00854

Species: Human

Expression System: E. coli

SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05498

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01357

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01363

Species: Human

Expression System: HEK293 Cells

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